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Welcome to the Blenis Lab

The Blenis Laboratory investigates how cells sense and integrate cues to maintain cellular homeostasis. Particularly, we are interested in understanding how these mechanisms are hijacked by cancer cells to promote tumorigenesis and drug resistance. Utilizing state of the art technologies, we observe and manipulate these pathways in a variety of cell-based and mouse models of cancer. Additionally, our lab has made invaluable contributions to and continues to pioneer research in the study of lymphangioleiomyomatosis (LAM), an orphan disease affecting women of childbearing age, and has established a unique mouse model for this disease. The Blenis Laboratory is a part of the Meyer Cancer Center at Weill Cornell Medicine, a newly established cancer center in the heart of NYC. Dr. Blenis heads the Department of Pharmacology at Weill Cornell Medicine and is affiliated with the Tri-Institutional training programs (centered among three premier New York Institutions: Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center and the Rockefeller University.)