Publication: Unique Metabolic Adaptations Dictate Distal Organ-Specific Metastatic Colonization. Cancer Cell
Blenis Lab receives a Starr Cancer Consortium Grant
Publication: Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling. Cell
Dr. Ana P. Gomes becomes one of the winners of the Bench to Bedside Initiative Tri-Institute Shark Thank.
Dr. Ana P. Gomes is selected as a 2017 STAT Wunderkind.
Blenis lab holds its first annual retreat at Orchard Hill Estate, Harriman, NY.
Publication: TOR, the Gateway to Cellular Metabolism, Cell Growth, and Disease. Cell
Dr. Ana P. Gomes receives a Susan Komen Postdoctoral Fellowship.
Dr. Ana P. Gomes receives a NIH K99/R01 Pathway to Independence Award from National Cancer Institute.
Publication: Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition. Molecular Cell
Publication: Adding Polyamine Metabolism to the mTORC1 Toolkit in Cell Growth and Cancer. Developmental Cell
Tanya Schild receives a Ruth L. Kirschstein National Research Service Award Individual Predoctoral Fellowship (F31).
Joana Nunes receives the Best Short Talk prize in the FEBS Advanced Lecture Course on Oncometabolism - From Conceptual Knowledge to Clinical Applications. Figueira da Foz, Portugal
Blenis Lab receives a Department of Defense grant from the Tuberous Sclerosis Complex Research Program.
Dr. Ana P. Gomes becomes one of the finalists for the Regeneron Prize for Creative Innovation.
Dr. Bethany Schaffer receives a Ruth L. Kirschstein National Research Service Award Individual Postdoctoral Fellowship (F32)
Joana Nunes receives the best oral presentation prize in the 37th annual Vincent du Vigneaud Memorial Research Symposium at Weill Cornell Medicine, New York.
Dr. Ana P. Gomes is selected for a short talk in the Keystone Symposia: Epigenetics and Human Disease: Progress from Mechanisms to Therapeutics
Dr. Gina Lee is selected for a short talk in the Keystone Symposia: PI3K Pathways in Immunology, Growth Disorders and Cancer.
Blenis Lab receives a R03 grant from NIH (National Cancer Institute).
Publication: mTORC1-Driven Tumor Cells Are Highly Sensitive to Therapeutic Targeting by
Antagonists of Oxidative Stress. Cancer Research
Blenis Lab renews its “Signal Transduction to p70-S6 Kinase 1” R01 grant from NIH (National Institute of General Medical Sciences)
Publication: Seeing mTORC1 specificity. Science
Dr. Anders Mutvei receives a fellowship from Vetenskapsrådet (Swedish Research Counsel)
Blenis Lab receives funding from Highline Therapeutics as part of the Highline Translational Alliance Program.
Dr. Gina Lee is invited to give a talk at the International Tuberous Sclerosis Complex Research Conference in the UK.
Publication: A nexus for cellular homeostasis: the interplay between metabolic and signal transduction pathways. Current Opinion in Biotechnology
Tanya Schild is selected for the Institutional predoctoral Ruth L. Kirschstein National Research Service Award Individual, T32 training grant
Publication: ERK reinforces actin polymerization to power persistent edge protrusion during motility. Science Signaling
Publication: Synthetic lethality of combined glutaminase and Hsp90 inhibition in mTORC1-driven tumor cells. PNAS
Publication: The mTORC1/S6K1 Pathway Regulates Glutamine Metabolism through the
eIF4B-Dependent Control of c-Myc Translation. Current Biology
Blenis Lab moves to Weill Cornell Medicine in New York from Harvard University.
Blenis Lab renews its “Mitogenic and Oncogenic Regulation of ERK/RSK Signaling” R01 grant from NIH (National Cancer Institute)
Publication: Rapamycin: one drug, many effects. Cell Metabolism.
Publication: Akt-ivation of RNA splicing. Molecular Cell
Dr. Gina Lee receives a postdoctoral fellowship from The Lymphangioleiomyomatosis (LAM) Foundation
Blenis Lab receives a new R01 to study lymphangioleiomyomatosis (LAM) from NIH (National Heart, Lung, and Blood Institute).
Dr. Gina Lee receives a postdoctoral fellowship from Tuberous Sclerosis Alliance
Dr. Michal Nagiec receives a Ruth L. Kirschstein National Research Service Award Individual Postdoctoral Fellowship (F32)
Publication: Integration of mTOR and estrogen-ERK2 signaling in lymphangioleiomyomatosis pathogenesis. PNAS
Publication: AKT facilitates EGFR trafficking and degradation by phosphorylating and activating PIKfyve. Science Signaling
Publication: Nutrient regulation of the mTOR complex 1 signaling pathway. Molecules and Cells
Publication: The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4. Cell
Publication: mTORC1 signaling aids in CADalyzing pyrimidine biosynthesis. Cell Metabolism
Publication: Metabolic stress controls mTORC1 lysosomal localization and dimerization by regulating the TTT-RUVBL1/2 complex. Molecular Cell
Dr. Jeannie Li receives a postdoctoral fellowship from Tuberous Sclerosis Alliance
Publication: Hippo-YAP and mTOR pathways collaborate to regulate organ size. Nature Cell Biology
Dr. Michelle Mendoza receives a NIH K01 Mentored Research Scientist Career Development Award from the National Cancer Institute.
Dr. Gina Lee receives a postdoctoral fellowship from the Next Generation Research Program, Korean Government
Dr. Michal Nagiec is selected for the T32 Dana Farber Tumor Cell Biology Postdoctoral Training grant.
Dr. Long He receives a WCI postdoctoral fellowship from Korean Research Institute of Bioscience and Biotechnology.
Publication: Down-regulation of CMTM8 induces epithelial-to-mesenchymal transition-like changes via c-MET/extracellular signal-regulated kinase (ERK) signaling. Journal of Biological Chemistry